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Science Corporation announced a $230 million Series C financing on March 5, 2026, to advance PRIMA, an implant intended to restore limited central vision for people with severe retinal degeneration. Despite the “brain implant” shorthand, PRIMA is placed beneath the retina, not in the brain. The round gives Science more capital for clinical work, manufacturing and regulatory submissions, but the device is not yet established as commercially available.
What Science raised and what the money is for
Science said the oversubscribed Series C included Khosla Ventures, Lightspeed Venture Partners, Y Combinator, IQT and Quiet Capital, among existing investors. The company says the financing brings its total capital raised since its 2021 founding to approximately $490 million. TechCrunch reported a post-money valuation of about $1.5 billion, attributing that figure to a source close to the company rather than to Science’s financing announcement.
Science says the new capital will support PRIMA commercialization, expanded clinical trials, manufacturing and infrastructure, as well as its broader neural-technology portfolio. The full $230 million is therefore not a launch budget for one device.
PRIMA is Science’s near-term commercial focus. The company also describes work on biohybrid neural interfaces, its Vessel organ-preservation and perfusion platform, a MEMS microfabrication foundry and a broader brain-computer-interface ecosystem. Science’s financing announcement outlines those uses.
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PRIMA is a retinal implant, not a cortical brain implant
PRIMA is a photovoltaic chip implanted under the retina in an area where light-sensing photoreceptors have been lost. A camera-equipped pair of glasses captures the scene and projects patterned near-infrared light onto the chip. The implant converts that optical energy into electrical stimulation of remaining retinal circuitry; signals then travel through the optic nerve to the brain.
- The surgeon places the small chip beneath the retina.
- The glasses capture visual information and encode it into projected near-infrared patterns.
- The chip uses that light for both power and stimulation.
- Retinal cells and the optic nerve carry the resulting signals to the brain.
The system is not a standalone implant. Patients need the companion glasses and processing system, and it can work only when enough retinal ganglion-cell circuitry and optic-nerve function remain. Science describes the system at its PRIMA technology page and patient information page.
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Who the first indication is for
The initial target is severe central vision loss caused by geographic atrophy associated with age-related macular degeneration. That is a narrower population than “people who are blind.” Trials in Stargardt disease and retinitis pigmentosa are being expanded, but those are clinical-development programs, not approved uses. The expanded study is listed at ClinicalTrials.gov.
What the PRIMAvera study actually found
The pivotal evidence was published online by The New England Journal of Medicine on October 20, 2025. PRIMAvera was an open-label, multicenter, prospective, single-group, baseline-controlled study funded by Science Corporation and the Moorfields National Institute for Health and Care Research Biomedical Research Centre.
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| Measure | Reported result |
|---|---|
| Participants implanted | 38 |
| Participants assessed at 12 months | 32 |
| Clinically meaningful improvement threshold | At least 0.2 logMAR |
| Responders among 12-month completers | 26 of 32 (81%) |
| Estimated response including missing-data analysis | 80% |
| Serious adverse events | 26 events in 19 participants |
Participants could read letters, numbers and words under study conditions, but the trial did not show restoration of ordinary natural eyesight. Mean peripheral natural visual acuity remained equivalent to baseline. Most serious adverse events occurred within two months of surgery. Six implanted participants were not assessed at 12 months, so the 80% figure is an estimate that accounts statistically for missing follow-up, not a claim that 80% of every implanted patient will experience the same benefit.
The study’s size and design also matter. Thirty-eight implants provide important early human evidence, but an open-label study without a randomized sham-control group cannot answer every question about durability, safety or real-world function. The peer-reviewed findings and funding disclosures are available in NEJM; the study is registered as NCT04676854.
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What patients may—and may not—expect
- Functional central vision: The demonstrated endpoint concerns visual acuity tasks such as reading symbols and words, not normal sight.
- Required wearable: The glasses are essential for capturing scenes, delivering power and generating the stimulation pattern.
- Anatomical requirements: A functioning optic nerve and usable downstream retinal circuitry are necessary.
- Surgery and rehabilitation: Implantation is invasive, and patients may need training to interpret the artificial visual signal.
- Unknown long-term performance: Twelve-month data do not establish lifetime durability, replacement procedures or outcomes if the glasses or software are discontinued.
Where regulatory approval stands
Science submitted a CE Mark application in Europe on June 23, 2025; an application is not the same as a granted CE Mark. Its March 2026 financing announcement described a European launch as expected or upcoming, not completed. In the United States, Science has described an FDA application and continuing regulatory discussions, but the cited materials do not establish FDA approval.
The company said PRIMA received FDA Breakthrough Device status in 2023. That designation can facilitate interaction with regulators; it does not authorize marketing or guarantee clearance. The company’s European filing is described at Science’s regulatory announcement.
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What “bringing it to market” still requires
- Regulatory authorization in each intended market.
- Repeatable surgical procedures and training for specialist retinal centers.
- Manufacturing scale, quality systems and reliable supply of the implant and glasses.
- Long-term safety surveillance and post-market support.
- Patient-selection protocols, rehabilitation services and follow-up care.
- Reimbursement decisions; regulatory clearance alone does not ensure insurance coverage.
Science has not publicly disclosed a consumer price in the cited announcements, and the financing does not establish how patients or health systems will pay for treatment.
Is Science ahead of Neuralink?
Science may have a plausible path to an earlier commercial product because PRIMA addresses a specific ophthalmic indication and already has published human results. Neuralink’s principal public programs involve implanted cortical interfaces aimed at communication or motor control for people with paralysis and other neurological conditions. Those systems face different surgeries, endpoints and regulatory questions.
That comparison should be made by category. PRIMA is a retinal vision prosthesis and can reasonably be described as a retinal BCI. It is not the same kind of cortical motor or communication implant associated with Neuralink. Science may be competing to commercialize a vision-restoration BCI, not necessarily to become the first invasive neural-interface company of every type.
Bottom line for investors and patients
The $230 million round materially strengthens Science’s ability to fund trials, manufacturing and regulatory work around PRIMA. The technology has encouraging but limited 12-month evidence: 26 of 32 assessed participants met the study’s improvement threshold, alongside 26 serious adverse events in 19 participants. The decisive milestones are still authorization, durable safety, repeatable surgery, reimbursement and proof that the artificial vision is useful beyond controlled testing.
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